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Michiko Aihara Selected Research

Stevens-Johnson Syndrome (Lyell's Syndrome)

9/2021A pediatric case of Stevens-Johnson syndrome with acute liver failure, resulting in liver transplantation.
1/2020Toxic epidermal necrolysis accompanied by several immune-related adverse events developed after discontinuation of nivolumab.
6/2019Case of toxic epidermal necrolysis occurring after bone marrow transplantation accompanied by engraftment failure.
1/2019The Medication Risk of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Asians: The Major Drug Causality and Comparison With the US FDA Label.
1/2019Association of HLA class I and II gene polymorphisms with acetaminophen-related Stevens-Johnson syndrome with severe ocular complications in Japanese individuals.
1/2018Specific association of the rs6500265 and rs9933632 single-nucleotide polymorphisms in Japanese patients with antipyretic analgesic-related Stevens-Johnson syndrome and toxic epidermal necrolysis with severe ocular involvements.
8/2015Efficacy of additional i.v. immunoglobulin to steroid therapy in Stevens-Johnson syndrome and toxic epidermal necrolysis.
8/2015Reduction of interleukin-10 production by B cells in intractable toxic epidermal necrolysis.
4/2015Non-drug-induced Stevens-Johnson syndrome successfully treated with high-dose i.v. immunoglobulin.
1/2015Development of a simple genotyping method for the HLA-A*31:01-tagging SNP in Japanese.
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Michiko Aihara Research Topics

Disease

23Stevens-Johnson Syndrome (Lyell's Syndrome)
09/2021 - 10/2007
22Atopic Dermatitis (Atopic Eczema)
09/2020 - 11/2002
21Hypersensitivity (Allergy)
11/2019 - 09/2004
9Psoriasis (Pustulosis Palmaris et Plantaris)
11/2020 - 01/2009
8Inflammation (Inflammations)
01/2019 - 01/2009
7Anaphylaxis (Anaphylactic Shock)
08/2020 - 03/2006
5Dermatitis
11/2015 - 11/2003
5Drug-Related Side Effects and Adverse Reactions
03/2015 - 12/2005
5Pruritus (Itching)
11/2014 - 12/2008
4Neoplasms (Cancer)
04/2021 - 02/2011
4Erythema
06/2019 - 01/2009
4Urticaria (Hives)
01/2019 - 06/2011
4Eosinophilia
03/2015 - 03/2005
3Allergic Contact Dermatitis
02/2021 - 03/2018
3Contact Dermatitis (Eczema, Contact)
01/2019 - 11/2013
3Bullous Pemphigoid (Pemphigoid)
07/2018 - 04/2015
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
04/2018 - 01/2009
3Food Hypersensitivity (Food Allergy)
07/2017 - 12/2009
3Infections
01/2017 - 09/2004
3Exanthema (Rash)
03/2011 - 03/2005
2Fibrosis (Cirrhosis)
01/2021 - 05/2018
2Wheat Hypersensitivity (Wheat Allergy)
11/2019 - 06/2014
2Blister (Bulla)
06/2019 - 07/2014
2Angioedema
06/2019 - 06/2011
2Bites and Stings (Sting)
07/2018 - 08/2014
2Systemic Scleroderma (Systemic Sclerosis)
05/2018 - 01/2017
2Asthma (Bronchial Asthma)
01/2017 - 06/2011
2Skin Diseases (Skin Disease)
11/2015 - 12/2008
2Bronchiolitis Obliterans
09/2015 - 07/2014
2Drug Hypersensitivity Syndrome
03/2015 - 01/2015
2Pemphigus (Pemphigus Vulgaris)
08/2014 - 07/2014
2Edema (Dropsy)
07/2014 - 03/2005
2Exercise-Induced Allergies
06/2014 - 12/2009
2Disease Progression
12/2005 - 09/2004
1Acute Liver Failure (Fulminant Hepatic Failure)
09/2021
1Liver Diseases (Liver Disease)
09/2021
1COVID-19
01/2021
1Arthritis (Polyarthritis)
11/2020
1Fasciitis (Fascitis)
11/2020
1Amyopathic dermatomyositis
10/2020
1Autoimmune Diseases (Autoimmune Disease)
09/2020
1Myositis (Idiopathic Inflammatory Myopathies)
05/2020
1Dermatomyositis (Dermatopolymyositis)
05/2020

Drug/Important Bio-Agent (IBA)

14Pharmaceutical PreparationsIBA
04/2019 - 09/2004
11Proteins (Proteins, Gene)FDA Link
09/2020 - 01/2009
11CytokinesIBA
01/2019 - 12/2005
7AllergensIBA
11/2018 - 03/2006
6Immunoglobulin E (IgE)IBA
07/2017 - 11/2003
5HLA-B Antigens (HLA-B)IBA
01/2019 - 11/2008
5AntigensIBA
04/2018 - 01/2009
5Biomarkers (Surrogate Marker)IBA
01/2017 - 01/2009
5Semaphorin-3AIBA
05/2013 - 12/2008
4GibberellinsIBA
08/2020 - 07/2017
4AntibodiesIBA
09/2015 - 06/2014
4Immunoglobulins (Immunoglobulin)IBA
08/2015 - 12/2005
4Carbamazepine (Tegretol)FDA LinkGeneric
01/2015 - 12/2005
4Nerve Growth Factor (NGF)IBA
05/2013 - 01/2009
3Messenger RNA (mRNA)IBA
01/2021 - 09/2012
3EnzymesIBA
09/2020 - 06/2014
3ImmunosorbentsIBA
09/2020 - 06/2014
3Imiquimod (Aldara)FDA LinkGeneric
01/2019 - 01/2015
3PeriostinIBA
05/2018 - 01/2015
3Interleukin-13IBA
04/2018 - 02/2005
3CollagenIBA
12/2017 - 05/2012
3ChemokinesIBA
12/2017 - 01/2015
3SteroidsIBA
08/2015 - 12/2008
2AutoantibodiesIBA
10/2020 - 07/2014
2transcriptional intermediary factor 1IBA
10/2020 - 05/2020
2Soaps (Soap)IBA
11/2019 - 01/2017
2Caveolin 1IBA
01/2019 - 11/2015
2Phenytoin (Dilantin)FDA LinkGeneric
01/2019 - 11/2013
2Interleukin-4 (Interleukin 4)IBA
04/2018 - 01/2018
2Chemokine CCL17IBA
12/2017 - 08/2014
2Cytidine Triphosphate (CTP)IBA
12/2017 - 05/2012
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
07/2017 - 12/2009
2Adrenal Cortex Hormones (Corticosteroids)IBA
10/2016 - 05/2009
2Ointments (Pastes)IBA
10/2016 - 10/2010
2Interleukin-10 (Interleukin 10)IBA
08/2015 - 03/2006
2Immunoglobulin G (IgG)IBA
08/2014 - 03/2005
2Allopurinol (Remid)FDA LinkGeneric
11/2013 - 11/2008
2MethylprednisoloneFDA LinkGeneric
11/2012 - 10/2007
2Interleukin-18 (Interleukin 18)IBA
05/2012 - 10/2010
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
06/2011 - 12/2009
2tributyltinIBA
09/2007 - 01/2006
1Bicarbonates (Hydrogen Carbonate)IBA
04/2021
1Glucose (Dextrose)FDA LinkGeneric
04/2021
1NitrogenIBA
04/2021
1Urea (Carbamide)FDA LinkGeneric
04/2021
1octyl 2-cyanoacrylateIBA
02/2021
1Bleomycin (Blenoxane)FDA LinkGeneric
01/2021
1DiamondIBA
01/2021
15,6-dihydroxy-2-dimethylaminotetralin (M 7)IBA
08/2020
1NivolumabIBA
01/2020

Therapy/Procedure

7Therapeutics
11/2020 - 02/2006
5Skin Care
04/2017 - 01/2014
4Aftercare (After-Treatment)
05/2020 - 09/2004
3Drug Therapy (Chemotherapy)
04/2017 - 01/2014
3Oral Administration
11/2014 - 05/2012
2Plasma Exchange
11/2012 - 09/2004
1Liver Transplantation
09/2021